Verified October 10, 2026 against the statutes, regulations and sources cited below. The state decides every application. All states
What testing sites miss in South Carolina
- Changes such as address, director, name or ownership go to the State Agency on the lab's letterhead with its CLIA number; PPM and Compliance director changes need the new director's qualifications.
Does South Carolina add a form to the CMS-116?
South Carolina mails an application packet on request (SC_CLIA@dph.sc.gov or (803) 545-4205) that contains required documents not available on the CMS website.
Where does a South Carolina CMS-116 go?
- South Carolina Department of Public Health, Healthcare Quality, Bureau of Nursing Homes and Medical Services
- Email: SC_CLIA@dph.sc.gov
- Phone: (803) 545-4203
Opening a testing site in South Carolina?
We prepare the CMS-116 and any South Carolina filing for your owner or director to sign, and track both to approval. You pay CMS and the state directly. A Certificate of Waiver application is $399 per site.